Endep

Who is Endep for ?

Amitriptyline, an antidepressant (mood elevator), is used to treat depression. this medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Amitriptyline also is used occasionally to treat chronic pain and eating disorders. Talk to your doctor about the possible risks of using this drug for your condition.

Amitriptyline helps treat depression by moderating certain chemicals in the brain (like serotonin and norepinephrine) that are responsible for mood.

When should I be careful taking Endep ?

Before taking amitriptyline,

• tell your doctor and pharmacist if you are allergic to amitriptyline or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription drugs you are taking or have taken within the last 2 weeks, especially anticoagulants [warfarin (Coumadin)]; antihistamines; cimetidine(Tagamet); estrogens; fluoxetine (Prozac); levodopa (Sinemet, Larodopa); lithium (Eskalith, Lithobid); MAO inhibitors [phenelzine (Nardil), tranylcypromine (Parnate)]; medication for high blood pressure, seizures, Parkinson's disease, diabetes, asthma, colds, or allergies; methylphenidate (Ritalin); muscle relaxants; oral contraceptives; sedatives; sleeping pills; thyroid medications; tranquilizers; and vitamins.
• tell your doctor if you have or have ever had glaucoma, an enlarged prostate, difficulty urinating, seizures, an overactive thyroid gland, or liver, kidney, or heart disease.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking amitriptyline, call your doctor immediately.
• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking amitriptyline.
• you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
• remember that alcohol can add to the drowsiness caused by this drug.
• tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of this drug.

Side Effects

Side effects from amitriptyline are common:

• upset stomach
• drowsiness
• weakness or tiredness
• excitement or anxiety
• insomnia
• nightmares
• dry mouth
• skin more sensitive to sunlight than usual
• changes in appetite or weight

Tell your doctor if any of these symptoms are severe or do not go away:

• constipation
• difficulty urinating
• frequent urination
• blurred vision
• changes in sex drive or ability
• excessive sweating

If you experience any of the following symptoms, call your doctor immediately:

• jaw, neck, and back muscle spasms
• slow or difficult speech
• shuffling walk
• persistent fine tremor or inability to sit still
• fever
• difficulty breathing or swallowing
• severe skin rash
• yellowing of the skin or eyes
• irregular heartbeat